Reference : Etude de l'infection rougeoleuse in vitro et de sa persistance dans les cellules nerv...
Scientific journals : Article
Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/3215
Etude de l'infection rougeoleuse in vitro et de sa persistance dans les cellules nerveuses en culture
French
[en] Study of Measles virus infection in vitro and of its persistence in nerve cells in culture
Rentier, Bernard mailto [Université de Liège - ULg > Laboratoire de Microbiologie générale et médicale > > >]
1981
Bulletin de l'Institut Pasteur
Elsevier
79
2
107-170
Yes
0020-2452
Paris
France
[en] Measles virus ; Viral persistence ; Nerve cell infection ; neurons ; latency
[fr] Rougeole ; Virus de la rougeole ; Infection de cellules nerveuses ; Latence virale ; Persistance virale
[en] Measles virus can infect neurons in culture. In mouse fetal neurons, infection is spontaneously persistent. Reactivation occurs very rarely. In human fetal neurons, infection is persistent if cells are cultured in human serum. However, if serum-free medium is used, infection becomes lytic and productive.Latency in mouse neurons is apparently due to the species barrier while latency in human neurons is induced by anti-measles virus antibodies contained in the serum. This might explain the difference between measles encephalitis and subacute sclerosing panencepalitis (SSPE), with presence of anti-measles antibody in the brain in the latter and not in the former.
Researchers
http://hdl.handle.net/2268/3215

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
RENTIER_B_1981_Bull Inst Pasteur_79_2_107.pdfNo commentaryAuthor postprint1.67 MBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.