Reference : Characterization of serracin P, a phage-tail-like bacteriocin, and its activity against ...
Scientific journals : Article
Life sciences : Microbiology
Life sciences : Biotechnology
http://hdl.handle.net/2268/32014
Characterization of serracin P, a phage-tail-like bacteriocin, and its activity against Erwinia amylovora, the fire blight pathogen
English
Jabrane, A. [> > > >]
Sabri, Ahmed mailto [Université de Liège - ULg > > Centre Wallon de biologie industrielle >]
Compère, Philippe mailto [Université de Liège - ULg > Département des sciences et gestion de l'environnement > Département des sciences et gestion de l'environnement >]
Jacques, P. [> > > >]
Vandenberghe, I. [> > > >]
Van Beeumen, J. [> > > >]
Thonart, Philippe mailto [Université de Liège - ULg > Département des sciences de la vie > Biochimie et microbiologie industrielles >]
Nov-2002
Applied and Environmental Microbiology
Amer Soc Microbiology
68
11
5704-5710
Yes (verified by ORBi)
International
0099-2240
Washington
[en] Serratia plymithicum J7 culture supernatant displayed activity against many pathogenic strains of Erwinia amylovora,the causal agent of the most serious bacterial disease of apple and pear trees, fire blight, and against Klebsiella pneumoniae, Serratia liquefaciens, Serratia marcescens, and Pseudomonas fluorescens. This activity increased significantly upon induction with mitomycin C. A phage-tail-like bacteriocin, named serracin P, was purified from an induced culture supernatant of S. plymithicum J7. It was found to be the only compound involved in the antibacterial activity against sensitive strains. The N-terminal amino acid sequence analysis of the two major subunits (23 and 43 kDa) of serracin P revealed high homology with the Fels-2 prophage of Salmonella enterica, the coliphages P2 and 168, the CTX prophage of Pseudomonas aeruginosa, and a prophage of Yersinia pestis. This strongly suggests a common ancestry for serracin P and these bacteriophages.
http://hdl.handle.net/2268/32014

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