ORBi: Verpoorte Robert - Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae)

Reference : Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae)


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Pharmacy, pharmacology & toxicology
	To cite this reference:	http://hdl.handle.net/2268/31569

Title :	Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae)
Language :	English
Author, co-author :	Verpoorte, Robert [> >]
	Frederich, Michel [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
	Delaude, Clément [> >]
	Angenot, Luc [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
	Dive, Georges [Université de Liège - ULg > > Centre d'ingénierie des protéines >]
	Thépenier, Philippe [> >]
	Jacquier, Marie-José [> >]
	Zèches-Hanrot, Monique [> >]
	Lavaud, Catherine [> >]
	Nuzillard, Jean-Marc [> >]
Publication date :	2010
Journal title :	Phytochemistry Letters
Publisher :	Elsevier Sequoia
Volume :	3
Pages :	100-103
Audience :	International
ISSN :	1874-3900
Keywords :	[en] Strychnos moandaensis ; moandaensine ; bisindole alkaloid ; anhydronium base ; antiplasmodial activity
Abstract :	[en] Moandaensine contains a rare anhydronium base subunit. It presents a moderate antiplasmodial activity with IC values of 11.2 microM and 9.2 microM against , respectively, the chloroquino sensitive FCA 20 GHA and chloroquino resistant W2 strains of Plasmodium falciparum
Permalink :	http://hdl.handle.net/2268/31569

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