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| Reference : Plasma Myeloperoxidase Level and Polymorphonuclear Leukocyte Activation in Horses Suffer... |
| Scientific journals : Article | |||
| Life sciences : Veterinary medicine & animal health | |||
| http://hdl.handle.net/2268/3150 | |||
| Plasma Myeloperoxidase Level and Polymorphonuclear Leukocyte Activation in Horses Suffering from Large Intestinal Obstruction Requiring Surgery: Preliminary Results | |
| English | |
Grulke, Sigrid  [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >] | |
| Benbarek, Hama [> > > >] | |
| Caudron, I. [> > > >] | |
| Deby-Dupont, G. [> > > >] | |
| Mathy-Hartert, M. [> > > >] | |
| Farnir, Frédéric [Université de Liège - ULg > Département de productions animales > Biostatistique, économie, sélection animale >] | |
| Deby, Christiane [Centre Hospitalier Universitaire de Liège - CHU > > Administration des patients - Admission des hospitalisés >] | |
| Lamy, Maurice [Université de Liège - ULg > Département des sciences cliniques > Anesthésie et réanimation] | |
| Serteyn, Didier [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >] | |
| Apr-1999 | |
| Canadian Journal of Veterinary Research = Revue Canadienne de Recherche Vétérinaire | |
| 63 | |
| 2 | |
| 142-7 | |
| Yes (verified by ORBi) | |
| International | |
| 0830-9000 | |
| [en] horse ; colic ; myeloperoxidase | |
| [en] Myeloperoxidase (MPO) is a specific enzyme of neutrophil azurophilic granules with a strong oxidative activity. Thanks to a radioimmunoassay of equine myeloperoxidase, the authors have observed a significantly higher plasma level of MPO in horses operated for strangulation obstruction of the large intestine (n = 6) than in horses suffering from a non-strangulating displacement of the large intestine (n = 9). For the 2 groups, 3 phases were distinguished: reception (P1), intensive care (P2) and terminal phase (P3). The mean peak values of MPO for these phases were 121.6 ng/mL (P1), 168.6 ng/mL (P2), and 107.0 ng/mL (P3) for the non-strangulating group, and 242.6 ng/mL (P1); 426.0 ng/mL (P2), and 379.5 ng/mL (P3) for the strangulation group. The variations of the mean peak values of plasma MPO were significantly different between the 2 groups and between the different phases. A significant increase of the least square means of MPO was observed between P1 and P2. A significant decrease of the least square means of the number of circulating leukocytes was observed between P1 and P3. Polymorphonuclear neutrophil activation could play a major role in the pathogenesis of acute abdominal disease and endotoxic shock. | |
| Researchers ; Professionals | |
| http://hdl.handle.net/2268/3150 |
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