Effect on insulin release of compounds structurally related to the potassium channel opener 7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide (BPDZ 73): introduction of heteroatoms on the 3-alkylamino side chain of the benzothiadiazine 1,1-dioxide ring
Boverie, S.; Antoine, M.-H.; De Tullio, Pascalet al.
2001 • In Journal of Pharmacy and Pharmacology, 53, p. 973-980
De Tullio, Pascal ; Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique
Somers, F.
Becker, B.
Sebille, S.
Lebrun, P.
Pirotte, Bernard ; Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique
Language :
English
Title :
Effect on insulin release of compounds structurally related to the potassium channel opener 7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide (BPDZ 73): introduction of heteroatoms on the 3-alkylamino side chain of the benzothiadiazine 1,1-dioxide ring
Allard B., Lazdunski M. (1993) Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells. Eur. J. Pharmacol. 236:419-426.
Bernardi H., Fosset M., Lazdunski M. (1988) Purification and affinity labelling of brain [3H] glibenclamide binding protein, a putative neuronal ATP-regulated K+ channel. Proc. Natl. Acad. Sci. USA 85:9816-9820.
Bryan J., Aguilar-Bryan L. (1997) The ABC of ATP-sensitive potassium channels: More pieces of the puzzle. Curr. Opin. Cell. Biol. 9:553-559.
Cook N.S. (1988) The pharmacology of potassium channels and their therapeutic potential. Trends Pharmacol. Sci. 9:21-28.
Cook D.L., Hales C.N. (1984) Intracellular ATP directly blocks K+ channels in pancreatic B-cells. Nature 311:271-273.
Cook N.S., Quast U. (1990) Potassium channel pharmacology. Potassium Channels, Structure, Classification, Function and Therapeutic Potential , In: Cook, N. S. (ed.); Ellis Horwood, Chichester, UK; 181-255.
De Tullio P., Pirotte B., Lebrun P., Fontaine J., Dupont L., Antoine M.-H., Ouedraogo R., Khelili S., Maggetto C., Masereel B., Diouf O., Podona T., Delarge J. (1996) 3- and 4 substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers: Synthesis, pharmacological evaluation and structure-activity relationships. J. Med. Chem. 39:937-948.
Di Bella M., Rinaldi M., Fabio U., Manicardi G. (1972) Azione antimicrobica di derivati dell' 1,2,4-benzothiadiazine-1,1-diossido. Il Farmaco. 27:990-998.
Girard Y., Atkinson J.G., Rokach J. (1979) A new synthesis of 1,2,4-benzothiadiazine and selective preparation of o-aminobenzenesulphonamides. J. Chem. Soc. Perkin. 1:1043-1047.
Hamilton T.C., Weston A.H. (1989) Cromakalim, nicorandil and pinacidil: Novel drugs which open potassium channels in smooth muscle. Gen. Pharmacol. 20:1-9.
Lebrun P., Devreux V., Hermann M., Herchuelz A. (1988) Pinacidil inhibits insulin release by increasing K+ outflow from pancreatic B-cells. Eur. J. Pharmacol. 156:283-286.
Lebrun P., Devreux V., Hermann M., Herchuelz A. (1989) Similarities between the effects of pinacidil and diazoxide on ionic and secretory events in rat pancreatic islets. J. Pharmacol. Exp. Ther. 250:1011-1018.
Lebrun P., Antoine M.-H., Herchuelz A. (1992) Minireview: K+ channel openers and insulin release. Life Sci. 51:795-806.
Lebrun P., Arkhammar P., Antoine M.-H., Nguyen Q.-A., Bondo Hansen J., Pirotte B. (2000) A potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin release. Diabetologia 43:723-732.
Leclerq-Meyer V., Marchand J., Woussen-Colle M.C., Giroix M.H., Malaisse W.J. (1985) Multiple effects of leucine on glucagon, insulin and somatostatin secretion from the perfused rat pancreas. Endocrinology 116:1168-1174.
Noma A. (1983) ATP-regulated K+ channels in cardiac muscle. Nature 305:147-148.
Pirotte B., De Tullio P., Lebrun P., Antoine M.-H., Fontaine J., Masereel B., Schynts M., Dupont L., Herchuelz A., Delarge J. (1993) 3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: A new class of potassium channel openers?. J. Med. Chem. 36:3211-3213.
Pirotte B., Antoine M.-H., De Tullio P., Hermann M., Herchuelz A., Delarge J., Lebrun P. (1994) A pyridothiadiazine (BPDZ 44) as a new and potent activator of ATP-sensitive K+ channels. Biochem. Pharmacol. 47:1381-1386.
Quayle J.M., Nelson M.T., Standen N.B. (1997) ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev. 77:1165-1232.
Wollweber H., Horstmann H., Stoepel K., Garthoff B., Puls H., Krause H.P., Thomas G. (1981) 3-Amino-2H-benzothiadiazin-1,1-dioxide mit antihypertensive und potentieller diabetogener Wirkung. Arzneim. Forsch. 31:279-288.
