Reference : Conditioning of and contextual sensitization to apomorphine-induced climbing in mice : e...
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/29426
Conditioning of and contextual sensitization to apomorphine-induced climbing in mice : evidence against the habitation hypothesis
English
Tirelli, Ezio mailto [Université de Liège - ULg > Département des sciences cognitives > Neuroscience comportementale et psychopharmacologie expér. >]
Heidbreder, C. [> > > >]
Apr-1999
Behavioral Neuroscience
113
2
368-376
Yes (verified by ORBi)
International
0735-7044
[fr] test
[en] Several predictions of the habituation hypothesis of conditioned drug effects were tested by looking at contextual sensitization to apomorphine-induced climbing in mice (Mus musculus). Mice were first sensitized to that effect after 9 daily injections of 0.4 mg/kg apomorphine in the test context. Other mice received the same treatment outside the test context. On Day 10, all mice were challenged with either saline (conditioned drug effects test) or apomorphine (contextual sensitization test). On both tests, the levels of climbing of mice that received apomorphine paired with the test context during the intermittent treatment were significantly higher than those of mice that were experiencing the test context for the first time (unexposed mice). Also, the rate of extinction in conditioned mice did not parallel the rate of habituation in the unexposed mice. Results contradict the habituation hypothesis of conditioned drug effects and contextual sensitization. ((c) 1999 APA/PsycINFO, all rights reserved)(journal abstract)
Centre de Neurosciences Cognitives et Comportementales
http://hdl.handle.net/2268/29426

There is no file associated with this reference.

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.