Reference : Vaccinia virus immune evasion
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/29199
Vaccinia virus immune evasion
English
Smith, G. L. [ > > ]
Symons, J. A. [ > > ]
Khanna, A. [ > > ]
Vanderplasschen, Alain mailto [Université de Liège - ULg > > Immunologie et vaccinologie >]
Alcami, A. [ > > ]
1997
Immunological Reviews
Munksgaard International Publishers
159
137-154
Yes (verified by ORBi)
International
0105-2896
1600-065X
Copenhagen
Denmark
[en] Vaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include proteins which oppose apoptosis. Synthesise steroids, capture chemokines, counteract complement, interfere with interferon and intercept interleukins. This review provides an overview of such proteins, with an emphasis on work from our laboratory, and illustrates how the study of these proteins can increase our understanding of virus pathogenesis, the function of the immune system and how to make safer and more immunogenic poxvirus-based vaccines.
Researchers ; Professionals
http://hdl.handle.net/2268/29199

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