Article (Scientific journals)
Eosinophilic Bronchopneumopathy in Dogs
Clercx, Cécile; Peeters, Dominique; Snaps, Frédéric et al.
2000In Journal of Veterinary Internal Medicine, 14 (3, May-Jun), p. 282-91
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Keywords :
eosinophilic; bronchopneumopathy; dog
Abstract :
[en] Eosinophilic bronchopneumopathy was diagnosed in 23 young dogs. Clinical signs included cough, gagging, and retching in all dogs, dyspnea in 21 dogs (91%), and nasal discharge in 12 dogs (52%). The most common radiographic findings were a moderate to severe bronchointerstitial pattern (68%, 13 of 19 dogs). Bronchoscopic findings included the presence of abundant yellow-green mucus or mucopurulent material (70%, 16 of 23 dogs) and severe mucosal thickening with an irregular or polypoid appearance (52%, 12 of 23 dogs), with partial airway closure during expiration in 3 dogs (13%). Peripheral blood eosinophilia was noted in 14 of 23 dogs (61%). Inflammatory cells in brush or bronchoalveolar lavage fluid cytologic preparations comprised more than 50% eosinophils in 14 of 23 dogs (61%), and 20-50% eosinophils in 6 dogs (26%). Eosinophilic infiltration of the bronchial mucosa was observed in biopsies from 19 dogs and was graded as mild (37%, 7 dogs), moderate (32%, 6 dogs), or severe (32%, 6 dogs). The mean serum immunoglobulin A concentration was almost double that of a population of 20 healthy dogs of various breeds. Oral glucocorticoids were administered on alternate days with progressive tapering of the dose; the dosage at maintenance varied between 0.1 and 1.0 mg/kg every other day. No relationship was found between the duration of clinical signs and the maintenance dosage or the cytologic and histopathologic grades.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Clercx, Cécile  ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux
Peeters, Dominique ;  Université de Liège - ULiège > Clinique des petits animaux
Snaps, Frédéric ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Imagerie médicale
Hansen, P.
Mc Entee, Kathleen ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Sémiologie et clinique médicale des petits animaux
Detilleux, Johann ;  Université de Liège - ULiège > Département de productions animales > Génétique quantitative
Henroteaux, Marc ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés
Day, M. J.
Language :
English
Title :
Eosinophilic Bronchopneumopathy in Dogs
Publication date :
2000
Journal title :
Journal of Veterinary Internal Medicine
ISSN :
0891-6640
eISSN :
1939-1676
Publisher :
Wiley, Malden, United States - Massachusetts
Volume :
14
Issue :
3, May-Jun
Pages :
282-91
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 May 2010

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