| Reference : Diversity of the Mechanisms of Resistance to Beta-Lactam Antibiotics |
| Scientific journals : Article | |||
| Life sciences : Biochemistry, biophysics & molecular biology | |||
| http://hdl.handle.net/2268/28922 | |||
| Diversity of the Mechanisms of Resistance to Beta-Lactam Antibiotics | |
| English | |
Frère, Jean-Marie [Université de Liège - ULg > > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines > >] | |
Joris, Bernard [Université de Liège - ULg > > Centre d'ingénierie des protéines >] | |
| Granier, B. [Université de Liège - ULG > > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines > >] | |
Matagne, André [Université de Liège - ULg > > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines > >] | |
| Ackerman, Francine [Centre Hospitalier Universitaire de Liège - CHU > > Cardiologie >] | |
| Bourguignon-Bellefroid, C. [Université de Liège - ULG > > Laboratoire d'Enzymologie, Centre d'Ingénierie des Protéines > >] | |
| 1991 | |
| Research in Microbiology | |
| 142 | |
| 6, Jul-Aug | |
| 705-10 | |
| International | |
| 0923-2508 | |
| [en] The sensitivity of a bacterium to beta-lactam antibiotics depends upon the interplay between 3 independent factors: the sensitivity of the essential penicillin-binding enzyme(s), the quantity and properties of the beta-lactamase(s) and the diffusion barrier that the outer-membrane of Gram-negative bacteria can represent. Those three factors can be modified by mutations or by the horizontal transfer of genes or portions of genes. | |
| http://hdl.handle.net/2268/28922 |
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