A Dorsomedial Subdivision within the Nucleus Intercollicularis Identified in the Japanese Quail (Coturnix Coturnix Japonica) by Means of Alpha 2-Adrenergic Receptor Autoradiography and Estrogen Receptor Immunohistochemistry
Ball, G. F.; Foidart, Agnès; Balthazart, Jacques
1989 • In Cell and Tissue Research, 257 (1), p. 123-8
[en] The nucleus intercollicularis is an important site in the control of vocalization in birds. In oscines, a subregion of the nucleus intercollicularis called the dorso-medial intercollicular nucleus appears to play a key role in this process because it receives the majority of the projections from the nucleus robustus archistriatalis and sends most of the projections to the motor nucleus of the hypoglossal nerve. In this paper, we present neurochemical studies of the nucleus intercollicularis in the Japanese quail which suggest the presence of heterogeneity within this structure. One rostral band contains high densities of cholinergic muscarinic receptors identified by quantitative autoradiography using tritiated N-methylscopolamine as the ligand. A caudal dorso-medial region is specifically labeled by estrogen receptors identified using immunocytochemistry and by alpha 2-adrenergic receptors which were quantified by autoradiography using tritiated para-amino-clonidine. This latter subregion is possibly equivalent to the dorso-medial intercollicular nucleus of oscines. Additional track-tracing studies should be performed to confirm this homology. The coexistence of estrogen and alpha 2-adrenergic receptors within the same structure suggests important functional connections between steroid action and catecholaminergic systems in the brain.
Foidart, Agnès ; Université de Liège - ULiège > Services généraux (Faculté de médecine) > Service administratif de la Faculté (Médecine)
Balthazart, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie de la différenciation sexuelle du cerveau
Language :
English
Title :
A Dorsomedial Subdivision within the Nucleus Intercollicularis Identified in the Japanese Quail (Coturnix Coturnix Japonica) by Means of Alpha 2-Adrenergic Receptor Autoradiography and Estrogen Receptor Immunohistochemistry
Adkins E.K. (1977) Effects of diverse androgens on the sexual behavior and morphology of castrated male quail. Horm Behav 8:201-207.
Adkins E.K., Pniewski E.E. (1978) Control of reproductive behavior by sex steroids in male quail. J Comp Physiol Psychol 92:1169-1178.
Arnold A.P., Nottebohm F., Pfaff D.W. (1976) Hormone concentrating cells in vocal control areas of the brain of the zebra finch (Poephila guttata). J Comp Neurol 165:487-512.
Ball G.F., Faris P.L., Hartman B.K., Wingfield J.C. (1988) Immunohistochemical localization of neuropeptides in the vocal control regions of two songbird species. J Comp Neurol 268:171-180.
GF.
.
.
.
Barfield R.J., Ronay G., Pfaff D.W. (1978) Autoradiographic localization of androgen-concentrating cells in the brain of the male domestic fowl. Neuroendocrinol 26:297-311.
Baylé J.D., Ramade F., Oliver J. (1974) Stereotaxic topography of the brain of the quail. J Physiol (Paris) 68:219-241.
Blaustein J.D. (1986) Cell nuclear accumulation of estrogen receptors in rat brain and pituitary gland after treatment with a dopamine-beta-hydroxylase inhibitor. Neuroendocrinology 42:44-50.
Blaustein J.D., Letcher B. (1987) Noradrenergic regulation of cytosol estrogen receptors in female rat hypothalamus: possible role of alpha 2-noradrenergic receptors. Brain Res 404:51-57.
Blaustein J.D., Turcotte J. (1987) Further evidence of noradrenergic regulation of rat hypothalamic estrogen receptor concentration: possible nonfunctional increase and functional decrease. Brain Res 436:253-265.
Bradford M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
Cohen J. (1983) Hormones and brain mechanisms of vocal behaviour in non-vocal learning birds. Hormones and behaviour in higher vertebrates , J., Balthazart, E., Prove, R., Gilles, Springer, Berlin; 422-436.
Cohen J., Cheng M.F. (1982) Effects of testosterone metabolites and estrogen in the midbrain control of courtship behavior in the male ring dove (Streptopelia risoria). Neuroendocrinology 34:64-74.
Gahr M., Konishi M. (1988) Developmental changes in estrogen sensitive cells in the forebrain of the zebra finch. Proc Natl Acad Sci USA 85:7380-7383.
Gahr M., Flügge G., Güttinger H.R. (1987) Immunocytochemical localization of estrogen binding neurons in the songbird brain. Brain Res 402:173-177.
Gahr M., Ball G.F., Schumacher M., Balthazart J. (1988) Neurochemical studies of the nucleus intercollicularis in the Japanese quail. Soc Neurosci [Abstr] 14:88.
Gurney M.E. (1981) Hormonal control of cell form and number in the zebra finch song sytem. J Neurosci 1:658-673.
Guyomarc'h J.C. (1974) Influence du benzoate d'œstradiol sur la fréquence et la hauteur des cris de contact chez la caille Japonaise. Bull Soc Zool France 4:743-751.
Johnson A.E., Nock B., McEwen B.S., Feder H.H. (1985) Estradiol modulation of α2-noradrenergic receptors in guinea pig brain assessed by tritium-sensitive film autoradiography. Brain Res 336:153-157.
Johnson A.E., Nock B., McEwen B.S., Feder H.H. (1988) α2- and α2-Noradrenergic receptors in steroid-sensitive brain areas: Development and response to estradiol-17α2 benzoate in neonatal guinea pigs. Developmental Brain Research 42:247-252.
Lücke J., Haase E. (1980) L.) nach Injektion von 3Autoradiographische Untersuchungen am Gehirn von Bergfinken (Fringilla montifringillaH-Testosteron. J Hirnforsch 21:369-380.
Martinez-Vargas M.C., Stumpf W.E., Sar M. (1976) Anatomical distribution of estrogen target cells in the avian CNS: a comparison with the mammalian CNS. The Journal of Comparative Neurology 167:83-104.
McEwen B.S., Parsons B. (1982) Gonadal steroid action on the brain: neurochemistry and neuropharmacology. Ann Rev Pharmacol Toxicol 22:555-598.
Nock B., Johnson A.E., Feder H.H., McEwen B.S. (1985) Tritiumsensitive film autoradiography of guinea pig brain α2-noradrenergic receptors. Brain Res 336:148-152.
Nock B., Ball G.F., Wingfield J.C., McEwen B.S. (1986) Regional localization of α1 and α2 adrenergic receptor binding in two species of wild songbird using tritium-sensitive film autoradiography. Soc Neurosci [Abstr] 12:143.
Nottebohm F., Kelley D.B., Paton J.A. (1982) Connections of vocal control nuclei in the canary telencephalon. J Comp Neurol 207:344-357.
Palkovits M. (1973) Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res 59:449-450.
Phillips R.E., Barfield R.J. (1977) Effects of testosterone implants in midbrain vocal areas of capons. Brain Res 122:378-381.
Schumacher M., Balthazart J. (1983) The effects of testosterone and its metabolites on sexual behavior and morphology in male and female Japanese quail. Physiol Behav 30:335-339.
Schumacher M., Balthazart J. (1985) Sexual differentiation is a biphasic process in mammals and birds. Neurobiology. Current comparative approaches , R., Gilles, J., Balthazart, Springer, Berlin Heidelberg New York; 203-219.
Schumacher M., Balthazart J. (1987) Neuroanatomical distribution of testosterone metabolizing enzymes in the Japanese quail. Brain Res 422:137-148.
Seller T.J. (1983) Control of sound production in birds. Bioacoustics: A comparative approach , B., Lewis, Academic Press, New York; 93-124.
Watson J.T., Adkins-Regan E. (1985) Autoradiographic localization of androgen and estrogen concentrating cells in the brain of the Japanese quail. Soc Neurosci [Abstr] 11:740.
Zigmond R.E., Nottebohm F., Pfaff D.W. (1973) Androgen-concentrating cells in the midbrain of a songbird. Science 179:1005-1007.