Article (Scientific journals)
Histopathological pattern and humoral immune response to a crude exo-antigen and purified keratinase of Microsporum canis in symptomatic and asymptomatic infected cats.
Mignon, Bernard; Coignoul, Freddy; Leclipteux, T. et al.
1999In Medical Mycology, 37 (1), p. 1-9
Peer Reviewed verified by ORBi
 

Files


Full Text
1998-Histopathological pattern and humoral immune response to a crude exo-antigen.pdf
Publisher postprint (10.25 MB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Animals; Antibodies, Fungal/blood; Antigens, Fungal/immunology; Cat Diseases/immunology/microbiology/pathology; Cats; Dermatomycoses/immunology/pathology/veterinary; Enzyme-Linked Immunosorbent Assay; Female; Male; Microsporum/enzymology/immunology; Peptide Hydrolases/immunology
Abstract :
[en] In order to understand better the mechanisms involved in the diverse clinical patterns in Microsporum canis-infected cats, the histopathological features were compared in symptomatic and asymptomatic infected cats. Additionally, the IgG immune response to a crude exo-antigen and purified keratinase of M. canis was studied by ELISA in cats of various clinical and mycological status. Acute and subacute perifolliculitis and folliculitis occurred more frequently in symptomatic than asymptomatic cats. The latter usually displayed signs of chronic inflammation and a marked infiltration of superficial dermis by mast cells, which would suggest that these animals present similarities to chronically dermatophytic humans or animals. When using a crude M. canis antigen, all infected cats were shown to have significantly higher levels of specific IgG when compared to culture negative and mechanical carrier-cats. In these non-infected animals, specific IgG was more frequently detected in adults than in young animals. No difference in anti-crude antigen specific IgG was observed between symptomatic and asymptomatic infected cats, indicating that the presence of IgG is probably unrelated to the clinical status of cats. Anti-keratinase specific IgG was only detected in one of the infected cats.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Mignon, Bernard ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires
Coignoul, Freddy ;  Université de Liège - ULiège > Département de morphologie et pathologie > Pathologie générale et autopsies
Leclipteux, T.
Focant, Charles ;  Université de Liège - ULiège > Département des sciences de la vie > Biologie et génétique moléculaire
Losson, Bertrand ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires
Language :
English
Title :
Histopathological pattern and humoral immune response to a crude exo-antigen and purified keratinase of Microsporum canis in symptomatic and asymptomatic infected cats.
Publication date :
1999
Journal title :
Medical Mycology
ISSN :
1369-3786
eISSN :
1460-2709
Publisher :
BIOS Scientific Publishers, Oxford, United Kingdom
Volume :
37
Issue :
1
Pages :
1-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 12 February 2010

Statistics


Number of views
76 (1 by ULiège)
Number of downloads
1 (1 by ULiège)

Scopus citations®
 
35
Scopus citations®
without self-citations
21
OpenCitations
 
2

Bibliography


Similar publications



Contact ORBi