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Field Efficacy of Injectable Moxidectin in Cattle Naturally Infested with Chorioptes Bovis and Sarcoptes Scabiei
Losson, Bertrand; Lonneux, J. F.
1993In Veterinary Parasitology, 51 (1-2), p. 113-21
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Abstract :
[en] Field efficacy of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bovis and Sarcoptes scabiei. Eight animals were allocated to two groups of four animals each, based on parasitological and clinical status. Animals of the treated group received one subcutaneous injection of injectable moxidectin at 0.2 mg kg-1 body weight on Day 0. Individuals of the control group received emergency treatment of a single injection of moxidectin at 0.2 mg kg-1 body weight on Day 28. Efficacy was assessed by (a) taking skin samples from each animal on Days 0, 7, 14, 21, 28, 42 and 56 and observing the numbers of viable mite stages and species and (b) clinical examination of animals on Days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated for each animal on Days 0, 28 and 56. On the basis of the geometric means from treated and control animals, the percentage reductions in the total numbers of living C. bovis mites on Days 7, 14, 21 and 28 were 69, 87, more than 99 and 98, respectively. However, at the end of the trial, only two animals were negative for C. bovis. The percentage reductions in the total numbers of S. scabiei on Days 7, 14, 21 and 28 were 93, 100, 100 and 100, respectively. Clinical indices of the treated animals showed a sharp decrease in the affected body surface area from a mean of 43.6% on Day 0 to 0.9% and 0% on Days 28 and 56, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Losson, Bertrand ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires
Lonneux, J. F.
Language :
English
Title :
Field Efficacy of Injectable Moxidectin in Cattle Naturally Infested with Chorioptes Bovis and Sarcoptes Scabiei
Publication date :
December 1993
Journal title :
Veterinary Parasitology
ISSN :
0304-4017
eISSN :
1873-2550
Publisher :
Elsevier, Netherlands
Volume :
51
Issue :
1-2
Pages :
113-21
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 09 November 2009

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