Reference : Melanin-concentrating hormone and immune function
Scientific journals : Article
Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/27633
Melanin-concentrating hormone and immune function
English
Lakaye, Bernard mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie humaine et pathologique >]
Coumans, Bernard mailto [Université de Liège - ULg > > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc. >]
Harray, Sophie [Université de Liège - ULg > > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc. >]
Grisar, Thierry mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie humaine et pathologique >]
2009
Peptides
Elsevier Science
30
2076-80
Yes (verified by ORBi)
International
0196-9781
New York
NY
[en] To date,melanin-concentrating hormone (MCH) has been generally considered as peptide acting almost
exclusively in the central nervous system. In the present paper, we revise the experimental evidence,
demonstrating that MCH and its receptors are expressed by cells of the immune system and directly
influence the response of these cells in some circumstances. This therefore supports the idea that, as with
other peptides, MCH could be considered as a modulator of the immune system. Moreover, we suggest
that this could have important implications in several immune-mediated disorders and affirm that there
is a clear need for further investigation
http://hdl.handle.net/2268/27633
10.1016/j.peptides.2009.05.004

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