Reference : Immunization and Dermatophytes
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
Human health sciences : Dermatology
http://hdl.handle.net/2268/27504
Immunization and Dermatophytes
English
Mignon, Bernard mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Tabart, Jérémy [> > > >]
Baldo, Aline mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Mathy, Anne mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Losson, Bertrand mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Vermout, Sandy [> > > >]
Apr-2008
Current Opinion in Infectious Diseases
21
2
134-140
Yes (verified by ORBi)
International
0951-7375
[en] PURPOSE OF REVIEW: Despite the availability of effective vaccines for certain animal species, vaccination against dermatophytosis requires improvement and further development in both animals and humans. This review provides an update on the current situation and focuses on recent advances in host-dermatophyte relationships that could have implications for future vaccination against the most prevalent of the fungal diseases. RECENT FINDINGS: Numerous dermatophytic virulence factors have recently been isolated and characterized at the molecular level, notably secreted proteases involved in the invasion of the keratin network. Their precise roles in the different steps of the infectious process and in immunopathogenesis are being studied, while all aspects of the host immune response against dermatophytes, including the innate response, are becoming increasingly documented. In addition, new molecular tools are now available for studying dermatophytes, which will accelerate research on this topic. SUMMARY: The growth of knowledge concerning all aspects of the host-dermatophyte relationship should contribute towards sound strategies for the development of effective and safe vaccines against dermatophytosis.
http://hdl.handle.net/2268/27504
10.1097/QCO.0b013e3282f55de6

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