Reference : Facteurs de virulence et propriétés spécifiques des souches invasives d'Escherichia c...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
Facteurs de virulence et propriétés spécifiques des souches invasives d'Escherichia coli : III) Production de toxines
[en] Virulence factors and specific properties of invasive Escherichia coli: III) Toxin production
Van Bost, S. [> > > >]
Mainil, Jacques mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Bactériologie et pathologie des maladies bactériennes >]
Annales de Médecine Vétérinaire
Annales Medecine Veterinaire
Yes (verified by ORBi)
[en] Escherichia coli bacterial species is subdivided into several strains that are pathogenic for man and animals, on the basis of their specific properties and factors which are responsible for their pathogenic characters. The pathogenic strains are classically subdivided into strains with intestinal tropism (enterotoxigenic, enteropathogenic, enterohaemmorrhagic, verotoxigenic and enteroinvasive) and with extraintestinal tropism (uropathogenic and invasive). Invasive strains cause septicaemia and/or bacteraemia with localisations in different internal organs (systemic infections). If specific virulence properties and factors of strains with intestinal tropism are quite well known and described, those of strains with extraintestinal tropism are much less characterised, especially in animals. The purpose of this serie of review articles is to present the current knowledge on specific properties and factors of extraintestinal strains: adhesins and colonisation factors, transmucosal transfer and survival in blood and internal organs, toxicity. The fourth manuscript will deal with the invasive strains themselves, focusing on the necrotoxigenic strains. This third manuscript presents the current knowledge on toxins produced by invasive strains of E. coli: endotoxins, cytotoxic necrotising factors, cytolethal distending toxins and haemolytic toxins.

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