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Article (Scientific journals)
Harm avoidance and serotonin.
Hansenne, Michel; Ansseau, Marc
1999In Biological Psychology, 51 (1), p. 77-81
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Keywords :
Adult; Female; Humans; Male; Personality Disorders/diagnosis/metabolism; Piperazines/pharmacology; Prolactin/metabolism; Questionnaires; Radioimmunoassay; Serotonin/metabolism; Serotonin Agonists/pharmacology
Abstract :
[en] The relationships between the Tridimensional Personality Questionnaire (TPQ) and serotonergic activity has been described in some studies with controversial results. These studies have focused on specific patient populations rather than normal controls. Therefore, the aim of the present study is to examine the relationships between the TPQ and serotonergic activity in a group of non-patient subjects. Twenty-three normal subjects answered the TPQ, and the serotonergic activity was assessed by the prolactin response to a highly potent and selective 5-HT1a agonist (flesinoxan). A positive relationship between harm avoidance and PRL response to flesinoxan was found. This study is consistent with the hypothesized link between serotonergic activity and the harm avoidance dimension of the biosocial model of Cloninger.
Research center :
Centre de Neurosciences Cognitives et Comportementales - ULiège
Disciplines :
Psychiatry
Author, co-author :
Hansenne, Michel  ;  Université de Liège - ULiège > Département des sciences cognitives > Psycho. de la personnalité et des différences individuelles
Ansseau, Marc ;  Centre Hospitalier Universitaire de Liège - CHU > Psychiatrie et psychologie médicale
Language :
English
Title :
Harm avoidance and serotonin.
Publication date :
1999
Journal title :
Biological Psychology
ISSN :
0301-0511
eISSN :
1873-6246
Publisher :
Elsevier Science, Amsterdam, Netherlands
Volume :
51
Issue :
1
Pages :
77-81
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 October 2009

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