[en] Acetaminophen/pharmacokinetics/poisoning ; Analgesics, Non-Narcotic/pharmacokinetics/poisoning ; Antidotes/therapeutic use ; Humans ; Poisoning/diagnosis/epidemiology/therapy ; Practice Guidelines as Topic
[en] Drug self-poisoning is a common cause of admission in ED. Among various incriminated substances, paracetamol is often implicated and presents a severe toxicity. We briefly describe the epidemiology and physiopathology of paracetamol self-poisoning. We then clarify the diagnostic elements, thresholds of toxicity, indications for treatment and different available therapeutic guidelines.