Reference : Pathogenesis of dermatophytosis
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/24988
Pathogenesis of dermatophytosis
English
Vermout, Sandy mailto [> > > >]
Tabart, Jeremy mailto [> > > >]
Baldo, Aline mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Mathy, Anne mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Losson, Bertrand mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Mignon, Bernard mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
2008
Mycopathologia
166
5-6
267-275
Yes (verified by ORBi)
International
0301-486X
Netherlands
[en] Animals ; Cat Diseases/microbiology/pathology ; Cats ; Dermatomycoses/microbiology/pathology/veterinary ; Epidermis/microbiology/pathology ; Host-Pathogen Interactions ; Humans ; Microsporum/pathogenicity/physiology ; Trichophyton/pathogenicity/physiology ; Virulence
[en] Despite the superficial localization of most dermatophytosis, host-fungus relationship in these infections is complex and still poorly elucidated. Though many efforts have been accomplished to characterize secreted dermatophytic proteases at the molecular level, only punctual insights have been afforded into other aspects of the pathogenesis of dermatophytosis, such as fungal adhesion, regulation of gene expression during the infection process, and immunomodulation by fungal factors. However, new genetic tools were recently developed, allowing a more rapid and high-throughput functional investigation of dermatophyte genes and the identification of new putative virulence factors. In addition, sophisticated in vitro infection models are now used and will open the way to a more comprehensive view of the interactions between these fungi and host epidermal cells, especially keratinocytes.
http://hdl.handle.net/2268/24988
10.1007/s11046-008-9104-5

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