Article (Scientific journals)
Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development
Manfroid, Isabelle; Caubit, Xavier; Marcelle, Christophe et al.
2006In Gene Expression Patterns, 6 (8), p. 908-912
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Keywords :
teashirt chick; mouse; Drosophila; Scleraxis; tendon; neurons
Abstract :
[en] Drosophila teashirt (tsh) is involved in the patterning of the trunk identity together with the Hox genes. In addition, it is also a player in the Wingless and the Hedgehog pathways. In birds and mammals, three Tshz genes are identified and the expression patterns for mouse Tshz1 and Tshz2 have been reported during embryogenesis. Recently, we showed that all three mouse Tshz genes can rescue the Drosophila tsh loss-of-function phenotype, indicating that the function of the teashirt genes has been conserved during evolution. Here we describe the expression pattern of chick TSHZ3 during embryogenesis. Chick TSHZ3 is expressed in several tissues including mesodermal derivatives, the central and peripheral nervous systems. Emphasis is laid on the dynamic expression occurring in regions of the somites and limbs where tendons develop. We show that TSHZ3 is activated in the somites by FGF8, a known inducer of the tendon marker SCX. (c) 2006 Elsevier B.V. All rights reserved.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Biochemistry, biophysics & molecular biology
Genetics & genetic processes
Author, co-author :
Manfroid, Isabelle ;  Université de Liège - ULiège > Département des sciences de la vie > Biologie et génétique moléculaire
Caubit, Xavier
Marcelle, Christophe
Fasano, Laurent
Language :
English
Title :
Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development
Publication date :
October 2006
Journal title :
Gene Expression Patterns
ISSN :
1567-133X
Publisher :
Elsevier Science Bv, Amsterdam, Netherlands
Volume :
6
Issue :
8
Pages :
908-912
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 09 February 2010

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