|Reference : Lumbosacral spinal evoked potentials in patients with multiple sclerosis.|
|Scientific journals : Article|
|Human health sciences : Neurology|
Social & behavioral sciences, psychology : Neurosciences & behavior
|Lumbosacral spinal evoked potentials in patients with multiple sclerosis.|
|Delwaide, P. [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Neuro-anatomie >]|
|Schoenen, Jean [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie CHR >]|
|De Pasqua, Victor [> > > >]|
|Lippincott Williams & Wilkins|
|Yes (verified by ORBi)|
|[en] Adolescent ; Adult ; Evoked Potentials ; Female ; Humans ; Male ; Middle Aged ; Multiple Sclerosis/physiopathology ; Reaction Time ; Spinal Cord/physiopathology|
|[en] Lumbosacral spinal evoked potentials were recorded percutaneously in 22 MS patients with spinal symptoms and in 24 age-matched normal volunteers. Latencies, durations, and areas of waves R and A (level S1) as well as S and P2 (level Th12) were analyzed. The most significant result observed in the MS group was a reduction of the ratio between the areas of P2 and S. The reduction was strongly correlated with intensity of spasticity, but not with other clinical features. The P2/S ratio can thus be proposed as an electrophysiologic measure of spasticity.|
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