Reference : Functional ANOVA with random functional effects: an application to event-related pote...
Scientific journals : Article
Human health sciences : Neurology
Physical, chemical, mathematical & earth Sciences : Mathematics
Functional ANOVA with random functional effects: an application to event-related potentials modelling for electroencephalograms analysis
Bugli, Céline [ > > ]
Lambert, Philippe mailto [Université de Liège - ULg > Institut des sciences humaines et sociales > Méthodes quantitatives en sciences sociales >]
Statistics in Medicine
Yes (verified by ORBi)
[en] EEG ; ERP ; P300 ; Mixed model ; P-splines ; Functional ANOVA
[en] The di erential e ects of basic visual or auditory stimuli on electroencephalograms (EEG), named event
related potentials (ERPs), are often used to evaluate the impact of treatments on brain performances. In
the present paper, we propose a P-splines based model that can be used to evaluate treatment e ect on
the timing and the amplitude of some peaks of the ERPs curves. Functional ANOVA is an adaptation
of linear model or analysis of variance to analyse functional observations. The changes in the functional
of interest e ects are generally described using smoothing splines. Eilers and Marx proposed to work
with P-splines, a combination of B-splines and di erence penalties on coe cients. We de ne a Psplines
model for ERPs curves combined with random e ects. In particular, we show that it is a useful
alternative to classical strategies requiring the visual and usually imprecise localization of speci c ERP
peaks from curves with a low signal-to-noise ratio.
Belgian state (Federal Office for Scientific, Technical and Cultural Affairs)
IAP network No. P5=24

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