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| Reference : From neurophysiology to genetics: cortical information processing in migraine underlies ... |
| Scientific journals : Article | |||
| Social & behavioral sciences, psychology : Neurosciences & behavior Human health sciences : Neurology | |||
| http://hdl.handle.net/2268/24204 | |||
| From neurophysiology to genetics: cortical information processing in migraine underlies familial influences--a novel approach | |
| English | |
| Sandor, P. S. [> > > >] | |
| Afra, J. [> > > >] | |
| Proietti Cecchini, A. P. [> > > >] | |
| Albert, A. [ > > ] | |
Schoenen, Jean  [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Neuro-anatomie] | |
| 2000 | |
| Functional Neurology | |
| 15 | |
| Suppl 3 | |
| 68-72 | |
| 0393-5264 | |
| [en] Migraine patients show impaired cortical information processing between attacks with deficient habituation of pattern-reversal visual evoked potentials (VEP), and strong intensity dependence of auditory cortical evoked potentials (IDAP). This could be a genetic trait as certain genetic patterns are known for evoked potentials in healthy subjects. VEP-habituation and IDAP were studied in 40 migraine patients, i.e. pairs of 20 parents and their children. We developed a novel approach based on Monte Carlo statistics to selectively assess vertical familial influences. Both groups, parents and children, were characterized by abnormal VEP-habituation and IDAP. However, similarity between related pairs was far more pronounced than similarity between unrelated pairs. Assessed with a novel statistical approach, familial influences proved to be highly significant in determining cortical information processing in migraineurs, thus supporting the important role of genetic factors. | |
| http://hdl.handle.net/2268/24204 |
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