|Reference : Reduced gating of middle-latency auditory evoked potentials (P50) in migraine patient...|
|Scientific journals : Article|
|Human health sciences : Neurology|
Social & behavioral sciences, psychology : Neurosciences & behavior
|Reduced gating of middle-latency auditory evoked potentials (P50) in migraine patients: another indication of abnormal sensory processing?|
|Ambrosini, A. [> > > >]|
|De Pasqua, Victor [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie CHR >]|
|Afra, J. [> > > >]|
|Sandor, P. S. [> > > >]|
|Schoenen, Jean [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Neuro-anatomie >]|
|Elsevier Scientific Publishers Ireland|
|Yes (verified by ORBi)|
|[en] Adult ; Auditory Perception/physiology ; Cerebral Cortex/pathology/physiopathology ; Evoked Potentials, Auditory/physiology ; Female ; Habituation, Psychophysiologic/physiology ; Humans ; Male ; Middle Aged ; Migraine Disorders/pathology/physiopathology ; Neural Inhibition/physiology ; Neural Pathways/pathology/physiopathology ; Reticular Formation/pathology/physiopathology|
|[en] Habituation of cortical evoked responses to repetitive stimuli is reduced in migraine between attacks. To explore another aspect of information processing, we measured auditory sensory gating. The amplitude of the P50 response to the second of two homologous stimuli was significantly less reduced in migraineurs than in healthy volunteers. This lack of auditory sensory gating may be due to a hypofunction of monoaminergic subcortico-cortical pathways, which is also supposed to cause the interictal deficit of cortical habituation to repetitive stimuli.|
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