Article (Scientific journals)
Risque de restenose et d'evenements cardiaques apres angioplastie coronaire chez le patient diabetique: reduction par des approches pharmacologiques systemiques.
Nyssen, Anne-Sophie; Legrand, Victor; Scheen, André
2009In Revue Médicale de Liège, 64 (4), p. 192-8
Peer reviewed
 

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Keywords :
Angioplasty, Balloon, Coronary/adverse effects; Anti-Inflammatory Agents/therapeutic use; Antioxidants/therapeutic use; Belgium/epidemiology; Cardiovascular Agents/therapeutic use; Coronary Restenosis/epidemiology/prevention & control; Coronary Thrombosis/therapy; Diabetes Complications/prevention & control; Diabetes Mellitus, Type 2/complications; Drug Therapy, Combination; Evidence-Based Medicine; Fatty Acids, Omega-3/therapeutic use; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use; Hypoglycemic Agents/therapeutic use; Immunologic Factors/therapeutic use; Incidence; Meta-Analysis as Topic; Platelet Aggregation Inhibitors/therapeutic use; Randomized Controlled Trials as Topic; Stents
Abstract :
[en] Various systemic pharmacological approaches have been evaluated to reduce the risk of restenosis after coronary angioplasty, with or without stent, in the general population and in diabetic patients who are at increased risk for such complication. The aim of the present paper is to describe the effects of the main pharmacological classes on the risk of restenosis, the need for new revascularisation procedures and the incidence of major clinical events (MACE: death, myocardial infarction, revascularisation). We will analyse the role of antiplatelet agents, omega-3 fatty acids, statins, anti-inflammatory compounds, immunomodulators, anti-oxidants, glitazones and, finally, classical antidiabetic drugs such as metformin and insulin. Whenever possible, we will focus our attention on the results obtained in the diabetic population.
Disciplines :
Endocrinology, metabolism & nutrition
Cardiovascular & respiratory systems
Author, co-author :
Nyssen, Anne-Sophie ;  Université de Liège - ULiège > Département Psychologies Cliniques et Systèmes Humains > Ergonomie et intervention au travail
Legrand, Victor ;  Université de Liège - ULiège > Département des sciences cliniques > Cardiologie
Scheen, André  ;  Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques
Language :
French
Title :
Risque de restenose et d'evenements cardiaques apres angioplastie coronaire chez le patient diabetique: reduction par des approches pharmacologiques systemiques.
Alternative titles :
[en] Incidence of restenosis and cardiac events after coronary angioplasty in diabetic patients: reduction by systemic pharmacological approaches
Publication date :
2009
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
ULg - Université de Liège, Liège, Belgium
Volume :
64
Issue :
4
Pages :
192-8
Peer reviewed :
Peer reviewed
Additional URL :
Available on ORBi :
since 25 September 2009

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