Article (Scientific journals)
Intranasal oxytocin in obsessive-compulsive disorder
Ansseau, Marc; Legros, Jean-Jacques; Mormont, Christian et al.
1987In Psychoneuroendocrinology, 12, p. 231-236
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Keywords :
oxytocin; obsessive-compulsive disorder; case report; treatment
Abstract :
[en] A 55 years patient with obsessive-compulsive disorder showed clear improvement during four weeks of treatment with intranasal oxytocin compared to four weeks of intranasal placebo. This improvement was concurrent with the development of severe memory disturbances, supporting the amnestic properties of the peptide. However, the patient also developped psychotic symptoms and a marked decrease in plasma sodium and osmolality, which may have masked the obsessive symptomatology. The case highlights the need for careful monitoring in long-term oxytocin therapy.
Disciplines :
Psychiatry
Author, co-author :
Ansseau, Marc ;  Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale
Legros, Jean-Jacques ;  Université de Liège - ULiège > Endocrinologie clinique
Mormont, Christian  ;  Université de Liège - ULiège > Faculté de médecine > Service de psychiatrie
Cerfontaine, Jean-Luc
Papart, Patrick ;  Université de Liège - ULiège > Psychiatrie et psychologie médicale
Geenen, Vincent ;  Université de Liège - ULiège > Centre d'immunologie - Embryologie
Franck, Georges 
Language :
English
Title :
Intranasal oxytocin in obsessive-compulsive disorder
Alternative titles :
[en] L'oxytocine intranasale dans les troubles obsessionnels et compulsifs
Publication date :
1987
Journal title :
Psychoneuroendocrinology
ISSN :
0306-4530
eISSN :
1873-3360
Publisher :
Pergamon Press - An Imprint of Elsevier Science, Oxford, United Kingdom
Volume :
12
Pages :
231-236
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 24 September 2009

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