Reference : Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol ...
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/23611
Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice
English
Debouck, C. [> > > >]
Haubruge, Eric mailto [Université de Liège - ULg > Gembloux Agro-Bio Tech > Gembloux Agro-Bio Tech >]
Bollaerts, P. [> > > >]
van Bignoot, D. [> > > >]
Brostaux, Yves mailto [Université de Liège - ULg > Gembloux Agro-Bio Tech > Gembloux Agro-Bio Tech >]
Werry, A. [> > > >]
Rooze, M. [> > > >]
2001
International Orthopaedics
Springer Verlag
25
3
194-198
Yes (verified by ORBi)
International
0341-2695
Berlin
Germany
[en] Kashin-Beck disease ; mycotoxin
[en] The contamination of drinking water by organic acids, selenium deficiency and the ingestion of fungal mycotoxins are the three main aetiological factors in the development of Kashin-Beck disease. An avian tibial chondrodysplasia induced by mycotoxins has been reported. Deoxynivalenol (DON) is one of many mycotoxins produced by the most common contaminating species of fungi. The pattern of skeletal malformations induced by its administration intraperitoneally to pregnant mice is reported. Costo-vertebral segmentation abnormalities were the main deformities observed. The chondrodysplasia previously described was not seen.
http://hdl.handle.net/2268/23611
10.1007/s002640100235
http://www.springerlink.com/content/6yfrev8btp6g6lr2/?p=bcf962bc036a45ae96e6382523b8712f&pi=16

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