Title : The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen.
Language : English
Author, co-author : Oury, Cécile [Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB > >]
Toth-Zsamboki, Emese [Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB > >]
Thijs, Chantal [Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB > >]
Vermylen, Jos [Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB > >]
Hoylaerts, Marc F [Katholieke Universiteit Leuven - KUL > Molecular and Cellular Medicine > CMVB > >]
Publication date : 2001
Journal title : Thrombosis and Haemostasis
Publisher : Schattauer Gmbh-Verlag Medizin Naturwissenschaften
Audience : International
ISSN : 0340-6245
City : Stuttgart
Country : Germany
Keywords : [en] platelet aggregation ; collagen ; purinergic receptors
Abstract : [en] This study shows that, during collagen-initiated platelet activation, the early secretion of ATP results in the activation of the P2X1 ion channel, which plays a role as a positive regulator of further platelet responses.
Permalink : http://hdl.handle.net/2268/23426