Reference : Relations entre immunogénicité et différenciation des métastases d'un mélanome expérimen...
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
http://hdl.handle.net/2268/23220
Relations entre immunogénicité et différenciation des métastases d'un mélanome expérimental chez la souris.
French
[en] Relation between immunogenicity and differentiation of metastasis in an experimental murine melanoma
Heinen, Ernst mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
Beckers, Josiane [Centre Hospitalier Universitaire de Liège - CHU > > Rééducation de la parole >]
Desaive, Claude [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Lennes, G. [> > > >]
Simar, L. [> > > >]
1982
Comptes Rendus des Séances de la Société de Biologie et de ses Filiales
176
2
223-6
0037-9026
[en] Animals ; Cell Differentiation ; Kinetics ; Melanoma/immunology/physiopathology ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis ; Neoplasms, Experimental/immunology/physiopathology
[en] The graft into the footpad of Jackson mice of B16 melanoma cells which are only slightly pigmented, induces the simultaneous appearance of achromatic and well-pigmented metastatics. We have analysed histologically both types of metastases from the 8th to the 20th day after the resection of the primary tumor. The percentages of mitoses are higher in the achromatic metastases than in the pigmented ones. Both are infiltrated by lymphocytes and by a small number of macrophages and polymorphonuclears. A statistical analysis demonstrates however that the percentage of lymphocytes is not related to the importance of the metastase pigmentation. The discussion is devoted to the relations between the infiltration by lymphocytes, the immunogenicity and the differentiation of the tumor.
http://hdl.handle.net/2268/23220

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