Article (Scientific journals)
Tolerance to the Foeto-Placental 'Graft': Ten Ways to Support a Child for Nine Months
Thellin, Olivier; Coumans, Bernard; Zorzi, Willy et al.
2000In Current Opinion in Immunology, 12 (6), p. 731-7
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Keywords :
feotus; allograft; th1/th/2
Abstract :
[en] Tolerance to the foetal 'allograft' has been extensively studied in the past few years, providing interesting new insights. In addition to a potential role for HLA-G, which has been widely discussed, there are hypotheses suggesting roles for several other molecules or cells: leukemia inhibitory factor and its receptor; indoleamine 2. 3-dioxygenase; the Th1/Th2 balance; suppressor macrophages; hormones such as progesterone or the placental growth hormone; CD95 and its ligand; and, as recently proposed, annexin II. Tolerance of the foetal allograft is probably the consequence of a wide panel of mechanisms that may or may not be pregnancy-specific, that are of major or secondary importance and that may be interconnected.
Disciplines :
Immunology & infectious disease
Author, co-author :
Thellin, Olivier ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine
Coumans, Bernard ;  Université de Liège - ULiège > CNCM/ Centre fac. de rech. en neurobiologie cell. et moléc.
Zorzi, Willy ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine
Igout, Ahmed ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Heinen, Ernst ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie humaine
Language :
English
Title :
Tolerance to the Foeto-Placental 'Graft': Ten Ways to Support a Child for Nine Months
Publication date :
December 2000
Journal title :
Current Opinion in Immunology
ISSN :
0952-7915
eISSN :
1879-0372
Publisher :
elsevier, London, United Kingdom
Volume :
12
Issue :
6
Pages :
731-7
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 26 November 2008

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