[en] Increasing interest in the role of omega 3 fatty acids has arisen in these latest years since evidence of their implication in the cardioprotective fish based diet of the Inuit has been demonstrated. Furthermore, several in vitro, in vivo and epidemiological studies support the benefit of this fatty acids intake in various pathological states such as in the cardiovascular, cancer, inflammation, psychiatric, paediatric, pulmonary, dermatological and ophthalmologic fields. This review will focus on metabolism and pharmacological implication of w3 fatty acids intake as well as its interest in the prevention or treatment of the above-mentioned pathologies.
Disciplines :
Pharmacy, pharmacology & toxicology Chemistry
Author, co-author :
Roland, Isabelle ; Centre Hospitalier Universitaire de Liège - CHU > Pharmacie
de Leval, X.
Evrard, Brigitte ; Université de Liège - ULiège > Département de pharmacie > Pharmacie galénique
Pirotte, Bernard ; Université de Liège - ULiège > Chimie pharmaceutique
Dogné, Jean-Michel ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Delattre, Luc ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Language :
English
Title :
Modulation of the arachidonic cascade with omega 3 fatty acids or analogues: Potential therapeutic benefits
Publication date :
August 2004
Journal title :
Mini Reviews in Medicinal Chemistry
ISSN :
1389-5575
Publisher :
Bentham Science Publ Ltd, Sharjah, United Arab Emirates