[en] The design of a hyperthermia applicator for heating biological tissues is presented in which the applicator consists of an array antenna surrounded by a perfect electrically conducting reflector. The heat hazard to superficial tissues is reduced by the introduction of a dielectric protecting layer over them. A method of moments formulation is applied to approximate the electric field within the biological medium and a closed form expression is presented for the electromagnetic coupling problem, which enables an optimisation procedure to be performed. The applicator enhances both penetration and focusing: deep tumours, close to the bone region, are heated and the percentage of biologically healthy tissue exposed to a specific absorption rate (SAR) hazard level diminishes by 53.8%.
Disciplines :
Electrical & electronics engineering
Author, co-author :
V Sabariego, Ruth ; University of Vigo, ETSE Telecomunicacion, Spain > Dept. of Communication Technologies > Antennas group
Landesa, Luis; University of Vigo, ETSE Telecomunicacion, Spain > Dept. of Communication Technologies > Antennas group
Obelleiro, Fernando; University of Vigo, ETSE Telecomunicacion, Spain > Dept. of Communication Technologies > Antennas group
Language :
English
Title :
Design of a microwave array hyperthermia applicator with a semicircular reflector
ADAIR, E. R. (1983): 'Microwaves and thermoregulation' (Academic Press), pp. 57-93
DURNEY, C. H. (1992): 'Antennas and other electromagnetic applicators in biology and medicine', Proc. IEEE, 80, pp. 194-199
FENN, A. J., POE, D. S., REUTER, C. E., and TAFLOVE A. (1993): 'Noninvasive monopole phased array for hyperthemia treatment of cranial-cavity and skull-based tumors: design, analysis and phantom tests', Proc. Ann. Int. Conf. IEEE Engineering in Medicine and Biology Society, 15, pp. 1453-1454
FENN, A. J., CHEUNG, A. Y., and CAO H. (1994): 'Adaptive focusing experiments for minimally invasive monopole phased arrays in hyperthermia treatment of breast cancer', Proc. Ann. Int. Conf. IEEE Engineering in Medicine and Biology Society, 16, pp. 766-767
GANDHI, O. P., LAZZI, G., and FURSE C. M. (1996): 'Electromagnetic absorption in the human head and neck for mobile telephones at 835 and 1900 MHz', IEEE Trans. Microw. Theory Tech., 44, pp. 1884-1897
GORDON SHORT, J., and TURNER P. F. (1980): 'Physical hyperthermia and cancer therapy', Proc. IEEE, 68, pp. 133-142
Harrington, R. F. (1993): 'Field computation by moment methods' (IEEE Press, New York)
HORNBACK, N. B. (1984): 'Hyperthermia and cancer: human clinical trial experience', Vol. 2 (CRC Press, Boca Raton)
JOINES, W. T., YANG ZHANG, CHENXING LI, and JIRTLE, R. L. (1994): 'The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz', Med. Phys., 21, pp. 547-550
KOTSUKA, Y., HANKUI, E., and SHIGEMATSU, Y. (1996): 'Development of ferrite core applicator system for deep-induction hyperthermia', IEEE Trans. Microw. Theory Tech, 44, pp. 1803-1809
LO, Y. T., LEE, S-W, and LEE Q. H. (1966): 'Optimization of directivity and signal-to-noise ratio of an arbitrary antenna array', Proc. IEEE, 54, pp. 1033-1045
LOANE III, J. T., and SHUNG-WU LEE (1989): 'Gain optimization of a near-field focusing array for hyperthermia applications', IEEE Trans. Microw. Theory Tech. 37, pp. 1629-1635
OKONIEWSKI, M., and STUCHLY M. A. (1996): 'A study of the handset antenna and human body interaction', IEEE Trans. Microw. Theory Tech., 44, pp. 1855-1864
RAPPAPORT C. M. (1989): 'Synthesis of optimum microwave antenna applicators for use in treating deep localized tumors', Chapter 2 in KONG, J. A. (Eds), 'Progress in electromagnetics research' PIER 1 (Elsevier, Cambridge)
REUTER, C. E., THIELE, E. T., TAFLOVE, A., PIKET-MAY, M., and FENN A. J. (1994): 'Linear superposition of phased array antenna near field patterns using the FD-TD method'. 10th Annual Review of Progress in Applied Computational Electromagnetics, Conference Proceedings, pp. 459-466
REUTER, C. E., TAFLOVE, A., SATHIASEELAN, V., PIKET-MAY, M., and MITTAL B. B. (1998): 'Unexpected physical phenomena indicated by FDTD modeling of the Sigma-60 deep hyperthermia applicator', IEEE Trans. Microw. Theory Tech., 46, pp. 313-319
RICHMOND J. H. (1965): 'Scattering by a dielectric cylinder of arbitrary cross section shape', IEEE Trans. Antennas Propag., AP-13, pp. 334-341