Reference : Deletion of a cyclic AMP receptor protein homologue diminishes germination and affect...
Scientific journals : Article
Life sciences : Microbiology
http://hdl.handle.net/2268/22664
Deletion of a cyclic AMP receptor protein homologue diminishes germination and affects morphological development of Streptomyces coelicolor
English
Derouaux, Adeline mailto [Université de Liège - ULg > > Centre d'ingénierie des protéines >]
Halici, S. [> > > >]
Nothaft, H. [> > > >]
Neutelings, Thibaut [Université de Liège - ULg > > Protéines et glycoprot. de matr.extracell. et membran.basal. >]
Moutzourelis, Georgios [Université de Liège - ULg > > Centre d'ingénierie des protéines >]
Dusart, Jean [> > > >]
Titgemeyer, F. [> > > >]
Rigali, Sébastien mailto [Université de Liège - ULg > > Centre d'ingénierie des protéines >]
Mar-2004
Journal of Bacteriology
Amer Soc Microbiology
186
6
1893-1897
Yes (verified by ORBi)
International
0021-9193
Washington
[en] Open reading frame SCO3571 of Streptomyces coelicolor encodes a protein of the cyclic AMP (cAMP) receptor protein (CRP) superfamily of regulatory proteins. A mutant revealed a dramatic defect in germination, followed by growth delay and earlier sporulation. This phenotype correlates with those of an adenylate cyclase (cya) mutant that cannot synthesize cAMP. This finding suggests that S. coelicolor may use a Cya-cAMP-CRP system to trigger complex physiological processes such as morphogenesis.
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http://hdl.handle.net/2268/22664

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