Reference : Phonological loop and central executive functioning in Alzheimer's disease
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/22571
Phonological loop and central executive functioning in Alzheimer's disease
English
Collette, Fabienne mailto [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie >]
Van der Linden, Martial mailto [Université de Liège - ULg > Département des sciences cognitives > Psychopathologie cognitive >]
Bechet, Sophie [Centre Hospitalier Universitaire de Liège - CHU > > Neurochirurgie >]
Salmon, Eric mailto [Université de Liège - ULg > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn. >]
Jul-1999
Neuropsychologia
Elsevier
37
8
905-918
Yes (verified by ORBi)
International
0028-3932
Oxford
[en] Alzheimers disease ; Working memory ; Phonological loop ; Central executive ; Heterogeneity
[de] Ka-ALZHEIMER'S DISEASE ; ka-central executive ; Ka-HETEROGENEITY ; Ka-PHONOLOGICAL LOOP ; Ka-WORKING MEMORY
[en] The phonological loop and central executive functioning were examined in patients with Alzheimer's disease (AD) and in normal elderly subjects. AD patients showed abnormal functioning of the phonological loop and decreased performance on tasks assessing the central executive. However, when AD patients were separated into two groups on the basis of their span level, both groups showed deficits of the central executive but only patients with the lower span level presented a dysfunction of the phonological loop as well as impaired performance in tasks of phonological discrimination, articulation rate and speed of processing. These results are interpreted in terms of progression of the disease, with high-span level patients being less severely demented and displaying deficits only in higher-level cognitive functions (such as manipulation of information stored in working memory) whereas patients with a low span level have impairments encompassing a series of more basic processes.
Researchers
http://hdl.handle.net/2268/22571
10.1016/S0028-3932(98)00148-1
http://www.elsevier.com/wps/find/journaldescription.cws_home/247/description#description

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