ORBi: Collie Gavin - Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes

Reference : Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes


	Document type :	Scientific journals : Short communication
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry
	To cite this reference:	http://hdl.handle.net/2268/22326

Title :	Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes
Language :	English
Author, co-author :	Collie, Gavin [ > > ]
	Reszka, Anthony P. [ > > ]
	Haider, Shozeb M. [ > > ]
	Gabelica, Valérie [Université de Liège - ULg > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.) >]
	Parkinson, Gary N. [ > > ]
	Neidle, Stephen [ > > ]
Publication date :	28-Dec-2009
Journal title :	Chemical Communications
Publisher :	Royal Society of Chemistry
Issue/season :	48
Pages :	7482-7484
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	1359-7345
e-ISSN :	1364-548X
City :	Cambridge
Country :	United Kingdom
Keywords :	[en] G-quadruplex ; DNA ; mass spectrometry ; ligand ; non-covalent ; structural biology
Abstract :	[en] Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.
Research units :	Giga-Systems Biology and Chemical Biology
Funders :	Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/22326
DOI :	10.1039/b901889a

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