You are here:
| Reference : Sciatic Nerve Regeneration through Venous or Nervous Grafts in the Rat |
| Scientific journals : Article | |||
| Human health sciences : Orthopedics, rehabilitation & sports medicine Human health sciences : Neurology | |||
| http://hdl.handle.net/2268/22278 | |||
| Sciatic Nerve Regeneration through Venous or Nervous Grafts in the Rat | |
| English | |
Foidart-Dessalle, Marguerite  [Université de Liège - ULg > Département des sciences de la motricité > Biomécanique >] | |
| Dubuisson, Annie [Centre Hospitalier Universitaire de Liège - CHU > > Neurochirurgie >] | |
| Lejeune, André [Université de Liège - ULg > Département Argenco : Secteur MS2F > Hydraulique génér., const. hydraul. et méc. des fluides >] | |
| Severyns, A. [> > > >] | |
| Manassis, Y. [> > > >] | |
| Delree, P. [> > > >] | |
| Crielaard, Jean-Michel [Université de Liège - ULg > Département des sciences de la motricité > Evaluation et entraînement des aptitudes physiques >] | |
| Bassleer, Roger [Université de Liège - ULg > > Relations académiques et scientifiques (Médecine) >] | |
| Lejeune, Georges [Université de Liège - ULg > > Relations académiques et scientifiques (Médecine) >] | |
| Nov-1997 | |
| Experimental Neurology | |
| 148 | |
| 1 | |
| 236-46 | |
| Yes (verified by ORBi) | |
| International | |
| 0014-4886 | |
| [en] This study analyses the interest of isologous venous grafts filled with saline or with Schwann cells versus nerve grafts as guides for regeneration of the sciatic nerve in 35 Wistar rats. Electrophysiological parameters (conduction velocities and distal latencies of motor responses) and the functional index of De Medinacelli were measured several times from 1 month to 1 year after surgery. An histological analysis was performed on 2 control rats and on 3 rats killed 6 or 12 months after surgery: the total number of fibers was counted on a montage photoprint of the whole nerve, and the diameters of axons and the thickness of the myelin sheath were measured on digitized images. With a portion of nerve as guide, the regeneration is faster than with a vein. However, regeneration after 6 months is at least as good with a venous graft filled with Schwann cells, as assessed by electrophysiological, functional, and histological analysis. The addition of Schwann cells in grafted veins allows the nerve to regenerate through longer gaps than previously described (25 vs 15 mm). In order to assess the quality of nerve regeneration, functional, electrophysiological, and histological analysis are complementary. | |
| Researchers ; Professionals ; Students | |
| http://hdl.handle.net/2268/22278 | |
| 10.1006/exnr.1997.6542 |
There is no file associated with this reference.
All documents in ORBi are protected by a user license.
