Reference : Polyamines in gut inflammation and allergy
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/22001
Polyamines in gut inflammation and allergy
English
Peulen, Olivier mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Deloyer, Patricia [> >]
Deville, Christelle [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Dandrifosse, Guy [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
2004
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents
Bentham Science Publishers Ltd.
3
1-8
Yes (verified by ORBi)
International
1568-0142
[en] polyamines ; GI Tract ; inflammation ; allergy ; probiotic
[en] The natural polyamines, named 1,4-diaminobutane, N-aminopropyl-1,4-diaminobutane and N,N'-bisaminopropyl- 1,4-diaminobutane, are also designated respectively as putrescine, spermidine and spermine. They are polycationic compounds found in all eukaryotic cells. As they are deeply involved in cell functions, e.g. cellular growth, their concentration and their equilibrium in the intracellular pool are maintained in very narrow limits by regulatory mechanisms acting in a very fast, sensitive and precise way. These compounds are involved in gut inflammatory processes and in allergy. Indeed, they control the production of inflammatory mediators in several cell lines or tissues. Polyamine metabolism could be considered as a putative target for inflammation, allergy prevention or therapy.
http://hdl.handle.net/2268/22001

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