Reference : Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of ur...

	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/21878

Title :	Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch
Language :	English
Author, co-author :	Claeys, Stéphanie [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie des animaux de compagnie > >]
	Rustichelli, Federico [> >]
	Noël, Stéphanie [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie et clinique chirurgicale des petits animaux > >]
	Hamaide, Annick [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie des animaux de compagnie > >]
Publication date :	May-2011
Journal title :	Canadian Veterinary Journal = Revue Vétérinaire Canadienne
Publisher :	Canadian Veterinary Medical Association
Volume :	52
Pages :	501-505
Audience :	International
ISSN :	0008-5286
City :	Ottawa
Country :	Canada
Keywords :	[en] Phenylpropanolamine ; Urinary incontinence ; Dogs ; Urodynamics
Abstract :	[en] Abstract The objective of this retrospective study was to report the efficacy of a single daily oral dose of phenylpropanolamine (PPA) in the treatment of urethral sphincter mechanism incompetence (USMI) in bitches. Nine bitches diagnosed with USMI were treated with a single daily dose (1.5 mg/kg) of PPA for at least 1 month. Urethral pressure profiles (UPP) were performed in 7 dogs before treatment and repeated in 4 of them after treatment. Treatment with PPA resulted in long-term continence in 8/9 bitches. One dog did not respond to PPA and was treated surgically later. Recheck UPPs showed a significant increase in maximal urethral closure pressure in the 4 bitches after treatment with PPA compared to before treatment. In conclusion, long-term continence can be achieved in bitches affected with USMI after administration of a single daily dose of PPA (1.5 mg/kg).
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/21878

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