Reference : Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of ur...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/21878
Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch
English
Claeys, Stéphanie mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie des animaux de compagnie > >]
Rustichelli, Federico [> >]
Noël, Stéphanie mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie et clinique chirurgicale des petits animaux > >]
Hamaide, Annick mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Chirurgie des animaux de compagnie > >]
May-2011
Canadian Veterinary Journal = Revue Vétérinaire Canadienne
Canadian Veterinary Medical Association
52
501-505
Yes (verified by ORBi)
International
0008-5286
Ottawa
Canada
[en] Phenylpropanolamine ; Urinary incontinence ; Dogs ; Urodynamics
[en] Abstract
The objective of this retrospective study was to report the efficacy of a single daily oral dose of phenylpropanolamine (PPA) in the treatment of urethral sphincter mechanism incompetence (USMI) in bitches. Nine bitches diagnosed with USMI were treated with a single daily dose (1.5 mg/kg) of PPA for at least 1 month. Urethral pressure profiles (UPP) were performed in 7 dogs before treatment and repeated in 4 of them after treatment. Treatment with PPA resulted in long-term continence in 8/9 bitches. One dog did not respond to PPA and was treated surgically later. Recheck UPPs showed a significant increase in maximal urethral closure pressure in the 4 bitches after treatment with PPA compared to before treatment. In conclusion, long-term continence can be achieved in bitches affected with USMI after administration of a single daily dose of PPA (1.5 mg/kg).
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/21878

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