Article (Scientific journals)
Concentration effects of selected insecticides on brain acetylcholinesterase in the common carp (Cyprinus carpio L.)
Dembele, K.; Haubruge, Eric; Gaspar, Charles
2000In Ecotoxicology and Environmental Safety, 45 (1), p. 49-54
Peer Reviewed verified by ORBi
 

Files


Full Text
Dembele_K_2000_EES_45_49.pdf
Author postprint (177.39 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Organophospbate; Carbamate; Synergy; AChE; Common carp
Abstract :
[en] The differential inhibition of acetylcholinesterase (AChE) by organophosphate (OP) and carbamate (C) is followed by the distinct duration of exposure effect on common carp AChE. Hence, in the present study in vivo exposure period effect and in vitro concentration-response of chlorfenvinphos, chlorpyrifos diazinon, and carbofuran were investigated on Cyprinus carpio L. AChE. Individuals of 1-year-old carp were exposed for 96 h to different concentrations of insecticides- after which AChE activity was measured in the brain. The highest concentrations of carbofuran (2.44 mg • L-1)- chlorfenvinphos (2.9 mgL-1), and diazinon (2.5 mg.L-1) killed at] the test animals after only 4 h, although there was no statistically significant difference from the control group's brain AChE activity. The lowest concentration significantly inhibited brain AChE after 96 h. Chlorfenvinphos was the most potent inhibitor in vivo and chlorpyrifos the least active inhibitor after 96 h of exposure time. In vitro experimentation with the same pesticide indicated that several concentrations inhibited 50% of the AChE activity (I50) ranging from 4.1 x 10-7 to 8.12X 10-4 M in both single inhibitory action and joint inhibitory effect. The results suggest that in biomonitoring programs carp brain AChE can be a good diagnostic tool for chronic OP nd C pollution.
Disciplines :
Environmental sciences & ecology
Author, co-author :
Dembele, K.
Haubruge, Eric  
Gaspar, Charles ;  Université de Liège - ULiège > Immunologie et vaccinologie
Language :
English
Title :
Concentration effects of selected insecticides on brain acetylcholinesterase in the common carp (Cyprinus carpio L.)
Publication date :
2000
Journal title :
Ecotoxicology and Environmental Safety
ISSN :
0147-6513
eISSN :
1090-2414
Publisher :
Elsevier science
Volume :
45
Issue :
1
Pages :
49-54
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 07 January 2018

Statistics


Number of views
64 (0 by ULiège)
Number of downloads
251 (0 by ULiège)

Scopus citations®
 
92
Scopus citations®
without self-citations
92
OpenCitations
 
57

Bibliography


Similar publications



Contact ORBi