Supercritical fluid chromatography: a promising alternative to current bioanalytical techniques

[en] During the last years, chemistry was involved in the worldwide effort toward environmental problems leading to the birth of green chemistry. In this context, green analytical tools were developed as modern Supercritical Fluid Chromatography in the field of separative techniques. This chromatographic technique knew resurgence a few years ago, thanks to its high efficiency, fastness and robustness of new generation equipment. These advantages and its easy hyphenation to MS fulfill the requirements of bioanalysis regarding separation capacity and high throughput. In the present paper, the technical aspects focused on bioanalysis specifications will be detailed followed by a critical review of bioanalytical supercritical fluid chromatography methods published in the literature.

Research center :

CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège

Disciplines :

Pharmacy, pharmacology & toxicology
Chemistry

Author, co-author :

Dispas, Amandine ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments

Jambo, Hugues ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique

André, Sébastien ; Université de Liège - ULiège > Master sc. pharma., à fin.

Tyteca, Eva ; Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes

Hubert, Philippe ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique

Language :

English

Title :

Supercritical fluid chromatography: a promising alternative to current bioanalytical techniques

Publication date :

January 2018

Journal title :

Bioanalysis

ISSN :

1757-6180

eISSN :

1757-6199

Publisher :

Future Science, London, United Kingdom

Volume :

Issue :

Pages :

107-124

Peer reviewed :

Peer Reviewed verified by ORBi

Name of the research project :

FEDER PHARE ULg Analytique

Funders :

FEDER - Fonds Européen de Développement Régional [BE]

Available on ORBi :

since 14 December 2017

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