Reference : Edible cyanobacterial genus Arthrospira: actual state of the art in cultivation metho...
Scientific journals : Article
Life sciences : Multidisciplinary, general & others
Life sciences : Biotechnology
Life sciences : Microbiology
http://hdl.handle.net/2268/216709
Edible cyanobacterial genus Arthrospira: actual state of the art in cultivation methods, genetics and application in medicine
English
[fr] Le genre de cyanobactérie comestible Arthrospira: état actuel des connaissances dans les méthodes de culture, la génétique et les applications dans le domaine médical
Furmaniak, Magda []
Misztak, Agnieszka []
Franczuk, Martyna []
Wilmotte, Annick mailto [Université de Liège - ULiège > Département des sciences de la vie > Physiologie et génétique bactériennes >]
Waleron, Malgorzata []
Waleron, Krzysztof []
In press
Frontiers in Microbiology
Frontiers Research Foundation
Yes (verified by ORBi)
International
1664-302X
Lausanne
Switzerland
[en] Arthrospira ; Spirulina ; cultivation ; toxins ; genetics ; applications
[fr] spiruline ; culture ; applications
[en] The cyanobacterial genus Arthrospira appears very conserved and has been divided into five main genetic clusters on the basis of
molecular taxonomy markers. Genetic studies of seven Arthrospira strains, including genome sequencing of seven strains, have
enabled a better understanding of those photosynthetic prokaryotes. Even though genetic manipulations have not yet been
performed with success, many genomic and proteomic features such as stress adaptation, nitrogen fixation or biofuel production
have been characterized. Many of above-mentioned studies aimed to optimize the cultivation conditions. Factors like the light
intensity and quality, the nitrogen source or different modes of growth (auto-, hetero- or mixotrophic) have been studied in
detail. The scaling-up of the biomass production using photobioreactors, either closed or open, was also investigated to increase
the production of useful compounds..
The richness of nutrients contained in the genus Arthrospira can be used for promising applications in the biomedical domain.
Ingredients such as the calcium spirulan, immulina, C‐phycocyanin and γ‐linolenic acid (GLA) show a strong biological activity.
Recently, its use in the fight against cancer cells was documented in many publications. The health-promoting action of 'Spirulina'
has been demonstrated in the case of cardiovascular diseases and age-related conditions. Some compounds also have potent
immunomodulatory properties, promoting the growth of beneficial gut microflora, acting as antimicrobial and antiviral. Products
derived from Arthrospira were shown to successfully replace biomaterial scaffolds in regenerative medicine. Supplementation
with the cyanobacterium also improves the health of livestock and quality of the products of animal origin. They were also used in
cosmetic preparations.
Centre d'Ingénierie des Protéines - CIP
Medical University of Gdansk, Poland
Arthrospira
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/216709

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