Article (Scientific journals)
Vignette therapeutique de l'etudiant Comment prescrire un medicament antidiabetique oral chez un patient diabetique de type 2 avec insuffisance renale ?
Scheen, André; Paquot, Nicolas
2017In Revue Médicale de Liège, 72 (10), p. 462-468
Peer reviewed
 

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Keywords :
Metformin; Renal insufficiency; SGLT2 inhibitor; Sulfonylurea; Type 2 diabetes; 4 inhibitor; DPP
Abstract :
[en] Patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) are increasingly numerous, especially in the elderly population. Surprisingly, this situation is often under-recognized or even neglected in clinical practice. Yet, most oral antidiabetic (OAD) agents have limitations in case of renal impairment, either because they require a dose reduction, or are contra-indicated mainly for safety reasons. This clinical case gives the opportunity to discuss the modalities of prescription and cautions to be taken when using most commonly prescribed OAD, metformin, insulin secretagogues (sulfonylureas, repaglinide), DPP-4 inhibitors (gliptins) and SGLT2 inhibitors, in a patient with T2D and CKD.
Disciplines :
Pharmacy, pharmacology & toxicology
Endocrinology, metabolism & nutrition
Author, co-author :
Scheen, André  ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Paquot, Nicolas ;  Université de Liège - ULiège > Département des sciences de la santé publique > Diabétologie, nutrition et maladies métaboliques
Language :
French
Title :
Vignette therapeutique de l'etudiant Comment prescrire un medicament antidiabetique oral chez un patient diabetique de type 2 avec insuffisance renale ?
Alternative titles :
[en] Use of oral glucose-lowering agents in patients with renal impairment
Publication date :
2017
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
72
Issue :
10
Pages :
462-468
Peer reviewed :
Peer reviewed
Additional URL :
Available on ORBi :
since 16 November 2017

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