Reference : Ex vivo expansion of hematopoietic progenitor cells is associated with downregulation of...
Scientific journals : Article
Human health sciences : Hematology
http://hdl.handle.net/2268/21181
Ex vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice
English
Foguenne, Jacques [Centre Hospitalier Universitaire de Liège - CHU > > Secteur assurance qualité >]
Di Stefano [> >]
Giet, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Thérapie cellulaire >]
Beguin, Yves [Université de Liège - ULg > Département des sciences cliniques > Hématologie - Oncologie médicale >]
Gothot, André mailto [Université de Liège - ULg > > Hématologie biologique et immuno hématologie >]
2009
Haematologica
Ferrata Storti Foundation
94
185-194
Yes (verified by ORBi)
International
0390-6078
1592-8721
Pavia
Italy
[en] stem cells ; hematopoiesis ; cell trafficking
[en] Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in engraftment of unmanipulated and cytokine-treated human cord blood CD34+ cells.
http://hdl.handle.net/2268/21181

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