Poster (Scientific congresses and symposiums)
Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Emmanuel, Noémie; Mendoza Gallego, Carlos; Lismont, Marjorie et al.
201620th Sigma-Aldrich Symposium
 

Files


Full Text
Emmanuel_Noemie_Sigma.pdf
Author postprint (735.81 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
(L)-methionine; microfluidics; continuous-flow; photooxidation; singlet oxygen
Abstract :
[en] Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side-reactions or product degradation due to overexposure. The recent implementation of photochemical processes in microreactors under continuous-flow conditions appeared to be much more powerful than its batch analogue in terms of irradiation efficiency and light penetration. Furthermore, the fine control of residence time ensures an accurate control of the irradiation time, avoiding side-reactions and degradation. The photooxidation of (L)-methionine with singlet oxygen using Rose Bengal as a sensitizer was successfully implemented in a microreactor setup and led to total and selective conversion into methionine sulfoxide, an important building block for the organic synthesis of peptides or functionalized amino acid. The reaction was performed in 2 min while the same reaction in batch took 2h.
Research center :
Center for Integrated Technology and Organic Synthesis
Disciplines :
Chemistry
Author, co-author :
Emmanuel, Noémie ;  Université de Liège > Département de chimie (sciences) > Center for integrated Technology and Organic Synthesis > Ph.D. Student (1st year)
Mendoza Gallego, Carlos ;  Université de Liège > Department of Chemical Engineering > Génie chimique - Nanomatériaux et interfaces
Lismont, Marjorie ;  Université de Liège > Département de physique > Biophotonique
Dreesen, Laurent ;  Université de Liège > Département de physique > Biophotonique
Heinrichs, Benoît ;  Université de Liège > Department of Chemical Engineering > Génie chimique - Nanomatériaux et interfaces
Monbaliu, Jean-Christophe  ;  Université de Liège > Département de chimie (sciences) > Centre for Integrated Technology and Organic Synthesis
Language :
English
Title :
Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Alternative titles :
[fr] Photoréacteur en continu intégré : Photooxydation de la (L)-méthionine avec de l'oxygène singulet
Publication date :
08 December 2016
Number of pages :
A5
Event name :
20th Sigma-Aldrich Symposium
Event organizer :
Sigma-Aldrich
Event place :
Blankenberge, Belgium
Event date :
du 08 décembre 2016 au 09 décembre 2016
Available on ORBi :
since 20 December 2016

Statistics


Number of views
84 (21 by ULiège)
Number of downloads
41 (11 by ULiège)

Bibliography


Similar publications



Contact ORBi