[en] In Alzheimer’s disease (AD), it is now well established that recollection is impaired from the beginning of the disease, whereas findings are less clear concerning familiarity. One of the most important mechanisms underlying familiarity is the sense of familiarity driven by processing fluency. In this study, we attempted to attenuate recognition memory deficits in AD by maximizing the salience of fluency cues in two conditions of a recognition memory task. In one condition, targets and foils have been created from the same pool of letters (Overlap condition). In a second condition, targets and foils have been derived from two separate pools of letters (No-Overlap condition), promoting the use of letter-driven visual and phonetic fluency. Targets and foils were low-frequency words. The memory tasks were performed by 15 patients with AD and 16 healthy controls. Both groups improved their memory performance in the No-Overlap condition compared to the Overlap condition. Patients with AD were able to use fluency cues during recognition memory as older adults did, but this did not allow to compensate for dysfunction of recognition memory processes.
Research center :
GIGA - CRC In vivo Imaging
Disciplines :
Theoretical & cognitive psychology
Author, co-author :
Simon, Jessica ; Université de Liège > Département de Psychologie > Département de Psychologie
Bastin, Christine ; Université de Liège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
SALMON, Eric ; Centre Hospitalier Universitaire de Liège - CHU > Service de neurologie
Willems, Sylvie ; Université de Liège > Clinique psychologique et logopédique universitaire (CPLU)
Language :
English
Title :
Increasing the salience of fluency cues does not reduce the recognition memory impairment in Alzheimer’s disease!
Publication date :
2018
Journal title :
Journal of Neuropsychology
ISSN :
1748-6645
eISSN :
1748-6653
Publisher :
British Psychological Society, Leicester, United Kingdom
Volume :
12
Pages :
216-230
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE] Fondation Recherche Alzheimer Pôle d'attraction interuniversitaire
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