The role of calcium supplementation in healthy musculoskeletal ageing - An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis ans Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF)
Harvey, N.C.; Biver, E.; Kaufman, J.-M.et al.
2017 • In Osteoporosis International, 28 (2), p. 447-62
[en] Abstract The place of calcium supplementation, with or
without concomitant vitamin D supplementation, has been
much debated in terms of both efficacy and safety. There have
been numerous trials and meta-analyses of supplementation
for fracture reduction, and associations with risk of myocardial
infarction have been suggested in recent years. In this report, the product of an expert consensus meeting of the
European Society for Clinical and Economic Aspects of
Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
(ESCEO) and the International Foundation for Osteoporosis
(IOF), we review the evidence for the value of calcium supplementation,
with or without vitamin D supplementation, for
healthy musculoskeletal ageing.We conclude that (1) calcium
and vitamin D supplementation leads to a modest reduction in
fracture risk, although population-level intervention has not
been shown to be an effective public health strategy; (2) supplementation
with calcium alone for fracture reduction is not
supported by the literature; (3) side effects of calcium supplementation
include renal stones and gastrointestinal symptoms;
(4) vitamin D supplementation, rather than calcium supplementation,
may reduce falls risk; and (5) assertions of increased
cardiovascular risk consequent to calciumsupplementation
are not convincingly supported by current evidence. In
conclusion, we recommend, on the basis of the current evidence,
that calcium supplementation, with concomitant vitamin
D supplementation, is supported for patients at high risk
of calcium and vitamin D insufficiency, and in those who are
receiving treatment for osteoporosis.
Disciplines :
Rheumatology Public health, health care sciences & services
Author, co-author :
Harvey, N.C. ✱
Biver, E. ✱
Kaufman, J.-M.
Bauer, J.
Branco, J.
Brandi, M. L.
Bruyère, Olivier ; Université de Liège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Coxam, V.
Cruz-Jentoft, A.
Czerwinski, E.
Dimai, H.
Fardellone, P.
Landi, F.
Reginster, Jean-Yves ; Université de Liège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
✱ These authors have contributed equally to this work.
Language :
English
Title :
The role of calcium supplementation in healthy musculoskeletal ageing - An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis ans Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF)
Publication date :
2017
Journal title :
Osteoporosis International
ISSN :
0937-941X
eISSN :
1433-2965
Publisher :
Springer Science & Business Media B.V., Godalming, United Kingdom
Volume :
28
Issue :
2
Pages :
447-62
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
The meeting was funded by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), a Belgian not-for-profit organisation.
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