Article (Scientific journals)
Polyphosphoesters: new trends in synthesis and drug delivery applications
Ergül, Zeynep; Jérôme, Christine
2016In Macromolecular Bioscience, 16 (12), p. 1745-1761
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Keywords :
biomaterial; nanomedicine
Abstract :
[en] Polymers with repeating phosphoester linkages in the backbone are biodegradable materials that emerge as a promising class of novel biomaterials, especially in the field of drug delivery systems. In contrast to aliphatic polyesters, the pentavalency of the phosphorus atom offers a large diversity of structures and as a consequence a wide range of properties for these mate- rials. In this paper, it is focused on the synthesis of well-defined polyphosphoesters (PPEs) by organocatalyzed ring-opening polymerization, improving the functionalities by combination with click reactions, degrada- tion of functional PPEs and their cytotoxicity, and inputs for applications in drug delivery.
Research center :
Center for Education and Research on Macromolecules (CERM)
CESAM - Complex and Entangled Systems from Atoms to Materials - ULiège
Disciplines :
Materials science & engineering
Chemistry
Author, co-author :
Ergül, Zeynep ;  University of Liège (ULg), Department of Chemistry, Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Jérôme, Christine  ;  University of Liège (ULg), Department of Chemistry, Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Polyphosphoesters: new trends in synthesis and drug delivery applications
Publication date :
December 2016
Journal title :
Macromolecular Bioscience
ISSN :
1616-5187
eISSN :
1616-5195
Publisher :
John Wiley & Sons, United Kingdom
Volume :
16
Issue :
12
Pages :
1745-1761
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
Available on ORBi :
since 23 September 2016

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