Article (Scientific journals)
Release of cardiac biomarkers during a cycling race
LE GOFF, Caroline; Kaux, Jean-François; D'OTREPPE DE BOUVETTE, Stéphanie et al.
2016In World Journal of Cardiovascular Diseases, 6 (8), p. 285-294
Peer reviewed
 

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Keywords :
cycling; cardiac biomarkers; stress biomarkers; renal function markers
Abstract :
[en] Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed in endurance sports events. The intense effort is not without risk. We aim to see if the relatively cardiospecific biomarkers could show the damage on cardiac muscle cells. Methods: Fourteen cyclists were recruited for an international race (177km). We studied the release of injury related cardiac markers, risk related cardiac markers, renal function markers and blood cytology. The subjects were submitted to three blood test: one before (T0), one just after (T1) and the last one 3 hours after the race (T3). Results: Blood cytology markers, namely erythrocytes, hemoglobin, hematocrit, and average hemoglobin concentration, were found to evolve in a similar way. Renal function markers, such as creatinin, cystatin C and uric acid, showed a post effort increase that might be related to renal blood flow depletion during exercise. Cardiac and muscular markers were all increased at T1. Conclusions: Physiological stress induced by an international cycling race certainly has consequences on cardiac muscle cells. Fortunately, those blood concentration variations are more representative of a transitional state, due to an imbalance created by an intense aerobic effort maintained during several hours, rather than an irreversible injury.
Disciplines :
Orthopedics, rehabilitation & sports medicine
Laboratory medicine & medical technology
Author, co-author :
LE GOFF, Caroline  ;  Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale
Kaux, Jean-François  ;  Université de Liège - ULiège > Département des sciences de la motricité > Département des sciences de la motricité
D'OTREPPE DE BOUVETTE, Stéphanie ;  Centre Hospitalier Universitaire de Liège - CHU > Pool
Goffaux, Sébastien
Fillet, Marianne ;  Université de Liège > Département de pharmacie > Analyse des médicaments
Chapelle, Jean-Paul ;  Université de Liège > Département de pharmacie > Département de pharmacie
Cavalier, Etienne  ;  Université de Liège > Département de pharmacie > Chimie médicale
Language :
English
Title :
Release of cardiac biomarkers during a cycling race
Publication date :
August 2016
Journal title :
World Journal of Cardiovascular Diseases
ISSN :
2164-5329
eISSN :
2164-5337
Publisher :
SCIRP, Irvine, United States - California
Volume :
6
Issue :
8
Pages :
285-294
Peer reviewed :
Peer reviewed
Available on ORBi :
since 22 September 2016

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