Systematic Downstream Development, Optimization and Equipment Design for Biobased Products and Processes

Biobased synthesis poses specific challenges due to the properties of raw materials, intermediates, and products. They are induced by the higher oxygen content as compared to fossil feedstock. Thus low vapor pressure, higher viscosity, low concentration in aqueous solution will require new, preferably liquid-based downstream processes, for which many different options can be proposed. A systematic method to evaluate such a multitude of options based on cascaded option trees is presented, which combines representation and evaluation of options on a suitably chosen level of detail. Criteria, which have to be fulfilled by the options, are flexibly evaluated ranging from input of experts to detailed simulation. Clear visualization also allows transparent communication of results to members of interdisciplinary teams and project partners.
The method is demonstrated for extractive separation steps including real-world problems encountered. This includes high viscosities, presence of solids or microorganisms leading to crud formation, and optimization of process conditions solving the conflicting challenges balancing e.g. between low toxicity to microorganisms and process efficiency.