Reference : Pseudomembranous colitis with Clostridium difficile during treatment by moxifloxacine...
Scientific congresses and symposiums : Poster
Human health sciences : Gastroenterology & hepatology
Human health sciences : Laboratory medicine & medical technology
http://hdl.handle.net/2268/1998
Pseudomembranous colitis with Clostridium difficile during treatment by moxifloxacine (quinolone)
English
Le Goff, Caroline mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Wiesen, Patricia [Centre Hospitalier Universitaire de Liège - CHU > > Soins intensifs >]
Collette, Julien [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Preiser, Jean-Charles [Centre Hospitalier Universitaire de Liège - CHU > > Soins intensifs >]
Kaux, Jean-François mailto [Université de Liège - ULg > Département des sciences de la motricité > Médecine physique et réadaptation fonctionnelle >]
De Mol, Patrick mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Microbiologie médicale et virologie médicale >]
27-Oct-2005
Yes
No
National
Symposium Annuel de la Société Belge de Biologie Clinique (S.B.B.C.)
27 octobre 2008
Liège
Begium
[en] Pseudomembranous colitis ; Clostridium difficile ; moxifloxacine
[en] C. difficile is the most frequently pathogenic agent isolated in colitis associated with antibiotics and pseudomembranous colitis (PMC). C. difficile takes advantage of the disturbance of the intestinal flora to settle.
We report a case of PMC appeared during treatment with moxifloxacine in a pulmonary infection in an emphysematous patient.
The diarrhea is generally benign, but can be severe, with toxic megacolon or even the extreme case of colic perforation.
The diagnosis is based on the research of toxins of C. difficile (A and/or B) in the intestinal stools or liquids (collected at the time of the endoscopic examination) to which is associated the anaerobic culture on selective agar. The reference method is the measurement of the cytotoxic effect of the B-toxin on a cell culture.
Metronidazole or vancomycine constitutes the treatment.
The prevention of relapses is very important, hygiene measures and probiotic agents must be associated to the antibiotic treatment.
Professionals ; Students
http://hdl.handle.net/2268/1998

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