Reference : The relationships between executive dysfunction and frontal hypometabolism in Alzheim...
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/19916
The relationships between executive dysfunction and frontal hypometabolism in Alzheimer's disease
English
Collette, Fabienne mailto [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie >]
Delrue, Gaël mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
Van der Linden, Martial mailto [Université de Liège - ULg > Département des sciences cognitives > Psychopathologie cognitive >]
Salmon, Eric mailto [Université de Liège - ULg > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn. >]
2001
Brain & Cognition
Academic Press
47
1/2
272-275
Yes (verified by ORBi)
International
0278-2626
1090-2147
New York
NY
[en] Alzheimer ; Disconnection ; Positron emission tomography
[en] A serie of tasks assessing executive functions was administered to patients with Alzheimer's disease and control subjects. Two groups of Alzheimer patients were examined : patients with hypometabolism restricted to the posterior (temporal and parietal) cerebral areas and patients with hypometabolism in both posterior and anterior (frontal) cerebral areas. The performance of Alzheimer patients was inferior to control subjects on all executive tasks. However, the two groups of Alzheimer patients did not differ from each other on all tasks except one. These data indicate that frontal lobe hypometabolism is not necessary to produce executive impairment in Alzheimer's disease. Consequently, executive dysfunction could be the consequence of a disconnection process between posterior and anterior cerebral areas;
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers
http://hdl.handle.net/2268/19916

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